Difference Between SUBOXONE® and Buprenorphine?

Suboxone and buprenorphine are the most significant medications used in drug addiction recovery. There are several differences and similarities between these two medications. Understanding the distinct features of these two medications is an integral part of addiction recovery.

Composition and ingredients

Suboxone is composed of buprenorphine and naloxone. The two medicines block the dangers of drug addiction on the brain. They attach to the opioid receptors in the brain and reduce the effects of opioids. This leads to decreased withdrawal symptoms and the urge to use opioids. They also reduce the euphoric effects of harmful opioids.

On the other hand, Buprenorphine is also used alone in MAT for opiate addiction. It is available without naloxone as a standalone medicine. However, its formulation without naloxone is less typically prescribed than Suboxone.


The suboxone doctors advise taking suboxone and buprenorphine sublingually. The medicines are placed under the tongue and are allowed to dissolve. This route of administration allows the drug to be swiftly absorbed into the bloodstream, relieving withdrawal symptoms of opiate addiction and decreasing cravings.

Use in MAT

The FDA has approved suboxone and buprenorphine as conventional drugs for treating opioid addiction. They are an essential part of MAT programs. To address addiction’s physical and psychological elements, MAT combines medicine with counseling and behavioral therapy, increasing the likelihood of effective recovery.

Risk of misuse and overdose

Naloxone present in the suboxone medication reduces the chances of overdose. After suboxone administration, the naloxone activates, increasing the withdrawal symptoms in opioid-dependent patients. Several healthcare practitioners recommend Suboxone due to its deterrent impact, which minimizes the danger of overdose and misuse.

Availability and prescription

Suboxone prescriptions can be obtained from healthcare and addiction specialists at addiction treatment centers. Suboxone contains naloxone, which requires a prescription. Buprenorphine, on the other hand, is a stand-alone medication. They are available in tablet and injectable form.

Individual Considerations

Prescribing suboxone and buprenorphine is a highly individualized process during opiate addiction recovery. They depend on factors such as the extent of addiction, previous treatment, and duration of treatment. Some people respond better to one medicine than another, and healthcare practitioners will adjust the treatment plan accordingly.


Suboxone and buprenorphine are essential components of opiate addiction recovery. The use of these two drugs increases the likelihood of long-term addiction recovery. Addiction recovery is difficult but not impossible. You may, however, overcome opioid addiction with the appropriate attitude and treatment.

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