Want to Know More about Opioids?

An Opioid is a chemical substance that creates pain relief or euphoric physical “highs” in the body. Opioid bind to receptors in the central nervous system and in other tissues to order to create that pain relief.

Opioids can be classified as natural, semi-synthetic, and fully-synthetic. Natural opioids include morphine, codeine, thebaine, and oripavine. Semi-sythetic opioids include hydrocodone, oxycodone, and heroin. Fully-synthetic opioids include fentanyl, pethidine, methadone, and propoxyphene.



Medical Use of Opioids

Opioids can also be medications derived from opium, which is collected from the seed pods of opium poppies. Opioid treatment, also known as narcotics, are most commonly used to treat moderate to severe pain. However, some less-potent forms are also used to treat conditions like coughing or diarrhea. They can come in various forms, from tablets and capsules to patches, injectables, and suppositories. Some commonly prescribed medications that fall into this category include:

  • Morphine (a.ka. MS Contin or Kadian)
  • Oxycodone (found in Percocet, Percodan, and Oxycontin)
  • Codeine (found in Tylenol #3 and prescription cough syrups)
  • Hydromorphone (a.k.a. Dilaudid)
  • Fentanyl (Duragesic in its patch form; Actiq as a transmucosal lozenge)
  • Hydrocodone (found in Vicodin and Lortab)
  • Methadone (potent painkiller also used to treat heroin addiction)
  • Meperidine (a.k.a. Demerol)


Opioids’ Effects

Opioids work in the body by attaching to the opioid receptors. The body stops perceiving pain when these receptors are blocked. Hence, the painkilling, euphoric “high.”

That euphoic “high” is opioids’ strongest effect. Unfortunately, many people abuse opioid addiction recovery specifically to get this feeling, leading to the severe problem of opioid addiction. It is estimated that approximately 9% of people have used opioid medications for the high, rather than the medicinal purpose.

Opioids’ Dangers

Many people who abuse opioids are unaware of the dangers these medications can pose. Opioids are nervous system depressants. This means that they slow down many of the body’s normal functions, including breathing. This can be extremely dangerous, especially when the medication is used in people who already have decreased respiratory function, or when mixed with other medications or alcohol. The symptoms of an opioid overdose include breathing that is slow and shallow, skin that has a bluish tone, coma, or even death. In addition, pregnant women who use opioid medications run the risk of delivering the baby prematurely or giving birth to an addicted infant who must undergo the painful and dangerous withdrawal process.

Opioids have many other side effects other than the feeling of euphoria. For example, they are often known to cause constipation. People who take long-acting or timed-release forms of the medications, such as Oxycontin, MS Contin and fentanyl patches are often prescribed a stool softener alongside to keep this side effect from creating a problem. Other common side effects are a loss of sex drive, irregularities in the menstrual cycle and mood swings.



Opioid Withdrawal

Opioid medications taken over a long period or for a chronic condition also make the body opioid medication on them. Even if it does not lead to addiction, the body experiences withdrawal symptoms when this happens. These symptoms can be severe and dangerous. Some of the symptoms found during withdrawal from opioids include:

  • Edginess and anxiety
  • Weepiness
  • Diarrhea
  • Cramping
  • Cravings
  • Insomnia
  • Muscle aches
  • Flu-like symptoms
  • Nausea and vomiting

It generally takes regular use over time before a person becomes physically dependent on the medication, but there is no set time. It’s completely dependent on the individual and several other factors, such as which medication is being taken, the strength of the medication, how accustomed the patient is to taking opioid medications and the route of administration.

As the body becomes more accustomed to the drug, the patient will find that more and more medication is required to help achieve the same effect. It can be a fine line for the doctor and patient to walk, as they try to use enough medication to effectively control the pain, while keeping physical dependence to a minimum. There is no reason, however, for a patient to suffer unduly. Part of a doctor’s job is to keep pain under control. This should be done if this means higher doses of opioid drugs, and the physical dependence aspect can be dealt with later.

A doctor who has prescribed opioids to treat a temporary condition, for example pain following surgery, will help the patient slowly wean down from the medication to prevent these withdrawal symptoms from becoming troublesome. Other medications, such as clonidine — a medication commonly used to treat blood pressure — are used to help the patient manage symptoms.





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